(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Basic information

Product Name:	(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid
Synonyms:	(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid;(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid;(1R,3S,4S)-N-(Tert-butoxycarbonyl)-2-azabicyclo-[2.2.1]-heptane-3-carboxylic acid;(1R,3S,4S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid 97%;2-Azabicyclo[2.2.1]heptane-2,3-dicarboxylic acid, 2-(1,1-diMethylethyl) ester, (1R,3S,4S)-;(1R,3S,4S)-3-[(2-methylpropoxy)carbonyl]-2-azabicyclo[2.2.1]heptane-2-carboxylic acid;Ledipasvir INT 2;Ledipasvir Impurity 14
CAS:	291775-59-2
MF:	C12H19NO4
MW:	241.28
EINECS:	808-164-2
Product Categories:	Heterocycles

(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Chemical Properties

Melting point	147-152 °C
Boiling point	371.0±25.0 °C(Predicted)
density	1.232±0.06 g/cm3(Predicted)
storage temp.	Sealed in dry,Room Temperature
pka	4.05±0.20(Predicted)
form	powder
optical activity	[α]22/D -170±10°, c = 1 in chloroform
InChIKey	IFAMSTPTNRJBRG-YIZRAAEISA-N

Safety Information

Hazard Codes	Xi,N
Risk Statements	61-36/37/38
Safety Statements	53-26-61
RIDADR	UN 3077 9/PG 3
WGK Germany	3

(3S)-N-Boc-2-azabicyclo[2.2.1]heptane-3-carboxylic acid Usage And Synthesis

Uses

(1R,3S,4S)-2-(tert-Butoxycarbonyl)-2-azabicyclo[2.2.1]heptane-3-carboxylic Acid is a building block in the synthesis of Ledipasvir, a potent, once-??daily oral NS5A inhibitor for the treatment of Hepatitis C Virus infection. It is also used to prepare potent direct inhibitors of factor Xa which carries significant promise for developing effective and safe anticoagulants.